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This case involves a 34-years-old male presenting primarily with prolonged weight loss exceeding 1 year and progressive jaundice over 1 month, following abrupt cessation of antithyroid medications

Groups that should avoid or seek clinician guidance first Pregnancy and breastfeeding: GHK-Cu has not been adequately studied in pregnancy or lactation

Those with Leber's disease (hereditary optic neuropathy) should avoid cyanocobalamin formulations

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Under hyperglycemic conditions, it substantially enhances the viability of human lens epithelial SRA01/04 cells and suppresses epithelial-mesenchymal transition (EMT) and oxidative damage by upregulating SIRT1 expression (Zeng et al., 2022)